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Research Overview

Active Research (10) | Completed Research (11)
Active Research (10)

Say No to Schistosoma
Start Date: Feb 2012
The mission of the Say No to Schistosoma project is to identify potential drug candidates that could possibly be developed into treatments for schistosomiasis. The extensive computing power of World Community Grid will be used to perform computer simulations of the interactions between millions of ... chemical compounds and certain target proteins. This will help find the most promising compounds that may lead to effective treatments for the disease.
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GO Fight Against Malaria
Start Date: Nov 2011
The mission of the GO Fight Against Malaria project is to discover promising new drug candidates that could be developed into new drugs that cure drug resistant forms of malaria. The computing power of World Community Grid will be used to perform computer simulations of the interactions between millions of ... chemical compounds and certain target proteins, to predict their ability to eliminate malaria. The best compounds will be tested and further developed into possible treatments for the disease.
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Drug Search for Leishmaniasis
Start Date: Aug 2011
The mission of Drug Search for Leishmaniasis is to identify potential drug candidates that could possibly be developed into treatments for Leishmaniasis. The extensive computing power of World Community Grid will be used to perform computer simulations of the interactions between millions of ... chemical compounds and certain target proteins. This will help find the most promising compounds that may lead to effective treatments for the disease.
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Computing for Clean Water
Start Date: Aug 2010
The mission of Computing for Clean Water is to provide deeper insight on the molecular scale into the origins of the efficient flow of water through a novel class of filter materials. This insight will in turn guide future development of low-cost and more efficient water filters.
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The Clean Energy Project - Phase 2
Start Date: Jun 2010
The mission of The Clean Energy Project is to find new materials for the next generation of solar cells and later, energy storage devices. By harnessing the immense power of World Community Grid, researchers can calculate the electronic properties of hundreds of thousands of organic ... materials – thousands of times more than could ever be tested in a lab – and determine which candidates are most promising for developing affordable solar energy technology.
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Help Cure Muscular Dystrophy - Phase 2
Start Date: May 2009
World Community Grid and researchers supported by Decrypthon, a partnership between AFM (French Muscular Dystrophy Association), CNRS (French National Center for Scientific Research), Universite Pierre et Marie Curie, ENS Lyon, Université Paris XI, Bordeaux 1, Lille 1 and IBM are investigating ... protein-protein interactions for more than 2,200 proteins whose structures are known, with particular focus on those proteins that play a role in neuromuscular diseases. The database of information produced will help researchers design molecules to inhibit or enhance binding of particular macromolecules, hopefully leading to better treatments for muscular dystrophy and other neuromuscular diseases.
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Help Fight Childhood Cancer
Start Date: Mar 2009
The mission of the Help Fight Childhood Cancer project is to find drugs that can disable three particular proteins associated with neuroblastoma, one of the most frequently occurring solid tumors in children. Identifying these drugs could potentially make the disease much more curable when ... combined with chemotherapy treatment.
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Help Conquer Cancer
Start Date: Nov 2007
The Ontario Cancer Institute (OCI), Princess Margaret Hospital and University Health Network have teamed with World Community Grid to improve the results of protein X-ray crystallography in order to increase understanding of cancer and its treatment.
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Human Proteome Folding - Phase 2
Start Date: Jun 2006
Human Proteome Folding Phase 2 (HPF2) continues where the first phase left off. The two main objectives of the project are to: 1) obtain higher resolution structures for specific human proteins and pathogen proteins and 2) further explore the limits of protein structure prediction by further developing Rosetta ... software structure prediction.
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FightAIDS@Home
Start Date: Nov 2005
FightAIDS@Home is a project focused on using computation methods to identify candidate drugs that have the right shape and chemical characteristics to block HIV protease. This approach is called "Structure-Based Drug Design", and according to the National Institute of General Medical Sciences, it has ... already had a dramatic effect on the lives of people living with AIDS.
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