From simulation to prediction: advances in understanding proteins

The Help Cure Muscular Dystrophy project finished its grid calculations last year. Team leader Dr. Alessandra Carbone has posted an update explaining her colleagues’ ongoing work on understanding and modeling the complex protein-protein interactions that lie behind diseases such as muscular dystrophy.

Dr. Carbone’s recent Help Cure Muscular Dystrophy project update explains several methods that she and her colleagues are exploring with the aim of improving their ability to both simulate and predict the interactions of proteins. This kind of improved modeling of proteins would make future research faster and open up entirely new research options, such as predicting the sites of protein interactions based solely on the genomic data that encodes that particular protein. Eventually, a better understanding of protein interactions could help researchers develop more effective treatments for neuromuscular diseases such as muscular dystrophy.
Dr. Carbone’s post gives another great example of how the work done on World Community Grid continues to have value for researchers long after the grid phase of the project is complete.

For further details, read Dr. Carbone’s update on her project website.

Related Articles