In this paper, the authors discuss Autophagy, a starvation induced cellular process of self-digestion that allows cells to degrade cytoplasmic contents.
"Therapeutic starvation and autophagy in prostate cancer: A new paradigm for targeting metabolism in cancer therapy"
Abstract:
Autophagy is a starvation induced cellular process of self-digestion that allows cells to degrade cytoplasmic contents. The understanding of autophagy, as either a mechanism of resistance to therapies that induce metabolic stress, or as a means to cell death, is rapidly expanding and supportive of a new paradigm of therapeutic starvation.
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