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200,000 Newly Predicted Protein Structures and Counting: The Microbiome Immunity Project's Plans for the Future
By: Tomasz Kosciolek, PhD
UC San Diego Center for Microbiome Innovation
23 Jul 2019   

Summary
The Microbiome Immunity Project has led to the prediction of almost 200,000 unique protein structures (so far), and the project has gone international. Learn more in this video update.

(The text below is a transcription of the video.)

Dear World Community Grid Volunteers,

As of July 2019, you’ve donated close to 70,000 CPU years to the Microbiome Immunity Project, which helped us to predict almost 200,000 unique protein structures!

At this time, this is more than all the experimentally solved protein structures to date!

Your generous contributions help us to develop new methods and gain insights regarding microbial proteins, their structural and functional universes.

We are constantly improving our methods thanks to the data generated by the project and learning from them to make adjustments to how and what we predict within the project. This way, it is a win-win situation: we constantly learn and innovate, while making the best use of the computing power you provide us with.

We are already annotating proteins with a state-of-the-art accuracy and discovering new structures that execute those functions. At the end of May, we met at the Flatiron Institute in New York to finalize a draft of a publication and to explore our findings to-date. Shortly, we will be sharing our findings in scientific publications and with you directly.

Ultimately, we are getting closer to addressing the main goal of this project - that is, microbiome immunity.

There is one more thing. As of last month I moved to Malopolska Center of Biotechnology in Kraków, Poland, to start an assistant professor position here. What does it mean for the project and my involvement in it? It’s good news, because here I am building a group to carry out even more work on this project. Soon, there will be more researchers working hard to make best use of the invaluable data you provide us with!

So thank you for participating in the project and making not only scientific discovery possible, but also building a truly international and collaborative network of researchers who are passionate and believe that the Microbiome Immunity Project is going to be transformative in our understanding of how the microbiome works and getting us closer to solving the microbiome immunity in Type-1 diabetes and inflammatory bowel disease.

Cześć!




Project Update

Tomasz Kosciolek, PhD
UC San Diego Center for Microbiome Innovation
Postdoctoral Research Associate