- What is malaria?
- How is malaria transmitted?
- How is malaria currently controlled?
- What are the symptoms of malaria?
- How many people are affected by malaria?
- Does malaria kill people?
- What areas of the world are affected by malaria?
- Is there a vaccine for malaria?
- What is the life cycle for the malaria parasite?
- What is GO Fight Against Malaria?
- What are multi-drug-resistant mutant superbugs?
- How do I join the GO Fight Against Malaria project?
- How does the GO Fight Against Malaria software work?
- What are AutoDock 4.2 and AutoDock Vina?
- How do these docking programs work?
- Will my device only be working on the GO Fight Against Malaria project?
- How can I learn more about malaria?
What is malaria?
How is malaria transmitted?
How is malaria currently controlled?
What are the symptoms of malaria?
How many people are affected by malaria?
Does malaria kill people?
What areas of the world are affected by malaria?
Malaria thrives in tropical and subtropical regions. Malaria infections are found in at least 106 different countries. It predominantly infects people in Africa, South-East Asia, and South America. However, in this era of globalization, it affects almost all sub-populations of the world, either physically, mentally, or monetarily. Millions of people from developed countries visit or work in malaria-infested regions each year.
Is there a vaccine for malaria?
What is the life cycle for the malaria parasite?
When an infected female mosquito bites someone’s skin, the Plasmodium parasite is injected. The parasite quickly invades liver cells (within a matter of minutes after it was injected). The parasite hides in the liver cells, where it undergoes asexual multiplication. This stage in the liver tends to last for eight to thirty days, during which the symptoms of malaria do not yet appear. The parasites escape the liver by rupturing the infected cells. The parasites then invade red blood cells, where they continue to undergo asexual multiplication. When these malaria parasites replicate themselves in red blood cells (which the parasites use for food and then burst), the symptoms of malaria appear (see the FAQ above on the symptoms of malaria). If another mosquito then feeds on that infected person’s blood, that mosquito becomes infected. Plasmodium parasites can only sexually reproduce when they are inside a mosquito.
What is GO Fight Against Malaria?
GO Fight Against Malaria is a project of the Olson laboratory (http://mgl.scripps.edu). The project uses distributed computing to help accelerate research on the discovery of new drugs which can cure infections of multi-drug-resistant mutant “superbugs” of Plasmodium falciparum, the parasite that causes the deadliest form of malaria.
What are multi-drug-resistant mutant superbugs?
How do I join the GO Fight Against Malaria project?
Detailed, step-by-step instructions are available at: http://www.worldcommunitygrid.org/reg/viewRegister.do. After installing BOINC and registering to become a member of World Community Grid, your computing device is then automatically put to work on these projects, and you can continue using your device as usual.
How does the GO Fight Against Malaria software work?
What are AutoDock 4.2 and AutoDock Vina?
These are two different types of “docking” programs, which allow us to computationally search for new compounds that might be able to bind to and block the activity of molecular drug targets from the malaria parasite. Both of these docking programs were created and developed by the Olson lab at The Scripps Research Institute (http://mgl.scripps.edu).