Although both projects relate to cancer research, the Help Conquer Cancer
project (run on World Community Grid from 2007-2013) focused on basic science - discovering principles of protein crystallization and helping to determine 3D structure of over 15,000 proteins. Knowing the protein structure helps scientists to understand their function and design drugs that may provide novel treatment options for multiple complex diseases, such as cancer.
The Mapping Cancer Markers project focuses on clinical application - discovering specific groups of markers that can be used to improve detection, diagnosis, prognosis and treatment of cancer. As a second goal, the comprehensive analysis of existing molecular profiles of cancer samples will lead to unraveling characteristics of such groups of markers - and in turn improving our understanding how to find them more efficiently.